Pubblichiamo questo importante studio segnalato dal Dott. Vincenzo Provenzano.   Oral Glucose-Lowering Agents vs Insulin for Gestational Diabetes Scarica il PDF Key Points Question  In gestational diabetes, is a sequential oral glucose-lowering medication strategy of metformin and additional glyburide, if needed, noninferior to insulin treatment for prevention of large-for-gestational-age infants? Findings  Among...

Riepilogo delle revisioni: Standard di cura nel diabete – 2025 SCARICA IL PDF Modifiche generali Il campo della cura del diabete sta cambiando rapidamente, poiché continuano a emergere nuove ricerche, tecnologie e trattamenti che possono migliorare la salute e il benessere delle persone con diabete. Con aggiornamenti annuali dal 1989,...

Abstract: Background: Surrogate indexes of insulin resistance (IR) are less expensive than the euglycemic glucose clamp. The simultaneous impact of sex and gender, smoking, and combined oral contraceptives (COC) on IR surrogate indexes was studied in a cohort of healthy young men and women (stratified in COC-free women and COC users). Methods: Glycemia,...

Riassunto e conclusioni articolo di Drucker su utilizzo GLP1 a.  Diabetes Care  (nov 2024) Più di 19 anni dopo la prima approvazione dell’exenatide due volte al giorno, nuovi farmaci GLP-1 più efficaci una volta alla settimana, esemplificati da semaglutide e tirzepatide, hanno ampliato l’interesse per l’efficacia a lungo termine e...

Neurodevelopmental Pathways to Obesity and Type 2 Diabetes: Insights From Prenatal Exposure to Maternal Obesity and Gestational Diabetes Mellitus: A Report on Research Supported by Pathway to Stop Diabetes Incidences of childhood obesity and type 2 diabetes (T2D) are climbing at alarming rates. Evidence points to prenatal exposures to maternal...

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Outcomes of Various Classes of Oral Antidiabetic Drugs on Nonalcoholic Fatty Liver Disease Key Points Question  Among sodium-glucose cotransporter 2 (SGLT2) inhibitors, thiazolidinediones, dipeptidyl peptidase-4 inhibitors, and sulfonylureas, which class of oral antidiabetic drugs (OADs) is the preferred therapeutic option for patients with both nonalcoholic fatty liver disease (NAFLD) and type...

The insulin resistant brain: impact on whole‑body metabolism and body fat distribution Abstract Insulin exerts its actions not only on peripheral organs but is also transported into the brain where it performs distinct functions in various brain regions. This review highlights recent advancements in our understanding of insulin’s actions within the brain,...

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